Differential interactions of conjugated polymer nanoparticles with glycosaminoglycans in synthetic urine.
نویسندگان
چکیده
Four different conjugated polymer nanoparticles (CPNs) were used to differentiate structurally similar glycosaminoglycans (GAGs) in a urine simulant. Unique emission response patterns of CPNs were analyzed by linear discriminant analysis (LDA), confirming that structurally diverse CPNs are sensitive and effective at differentiating GAGs in a complex biological medium.
منابع مشابه
Conjugated Polymer Nanoparticles for Label‐Free and Bioconjugate‐Recognized DNA Sensing in Serum
Hybridbio/-synthetic sensory conjugated polymer nanoparticles (CPNs) are developed for selective label-free detection of target ssDNA in serum. Carboxylic acid-functionalized anionic polyfluorene nanoparticles are rationally designed as signal amplifying unit to bioconjugate with amine functionalized single stranded oligonucleotides as a receptor. The covalent DNA coating can significantly impro...
متن کاملDestruction of Amylopectin in the Presence and Absence of TiO2 Nanoparticles
Today, the use of natural polymers and their replacement with synthetic polymers in various fields of science has attracted much attention. Reducing the associated risks, easy access, and being cost-effective are among the advantages of using natural polymers compared to the synthetic polymers. In this research, the destruction of amylopectin in the presence and absence of titanium dioxide nano...
متن کاملControlling photophysical properties of ultrasmall conjugated polymer nanoparticles through polymer chain packing
Applications of conjugated polymer nanoparticles (Pdots) for imaging and sensing depend on their size, fluorescence brightness and intraparticle energy transfer. The molecular design of conjugated polymers (CPs) has been the main focus of the development of Pdots. Here we demonstrate that proper control of the physical interactions between the chains is as critical as the molecular design. The ...
متن کاملBeyond superquenching: hyper-efficient energy transfer from conjugated polymers to gold nanoparticles.
Gold nanoparticles quench the fluorescence of cationic polyfluorene with Stern-Volmer constants (KSV) approaching 1011 M-1, several orders of magnitude larger than any previously reported conjugated polymer-quencher pair and 9-10 orders of magnitude larger than small molecule dye-quencher pairs. The dependence of KSV on ionic strength, charge and conjugation length of the polymer, and the dimen...
متن کاملA controllable approach to development of multi-spectral conjugated polymer nanoparticles with increased emission for cell imaging.
The authors demonstrate a smart and versatile approach for preparing multi-spectral conjugated polymers from a commercial precursor MEH-PPV without tedious synthetic modification. Multi-color CPNs with small size have also been successfully prepared using a modified-reprecipitation procedure for live cell imaging.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Chemical communications
دوره 51 19 شماره
صفحات -
تاریخ انتشار 2015